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Density00:56

Density

19.9K
Density is an important characteristic of substances, crucial in determining whether an object sinks or floats in a fluid. Its SI unit is kg/m3, and its cgs unit is g/cm3. The density of an object helps in identifying its composition, and also reveals information about the phase of the matter and its substructure. The densities of liquids and solids are roughly comparable, consistent with the fact that their atoms are in close contact. However, gases have much lower densities than liquids and...
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Current Density01:21

Current Density

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The total amount of current flowing through one unit value of a cross-sectional area is referred to as current density. If the current flow is uniform, the amount of current flowing through a conductor is the same at all points along the conductor, even if the conductor area varies. The current density consists of the local magnitude and direction of the charge flow, which varies from point to point. Current density is measured in amperes per meter square, and direction is defined as the net...
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Colors and Magnetism03:02

Colors and Magnetism

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Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...
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Strain-Energy Density01:20

Strain-Energy Density

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Understanding the strain energy density in materials under axial load is crucial for evaluating their mechanical behavior and durability. When a rod is subjected to such a load, it elongates and stores energy, known as strain energy, as potential energy within the material. This energy is measured in terms of energy per unit volume.
In the elastic region of a material, the relationship between the stress and the strain is linear and follows Hooke's Law. The strain energy density in this region...
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Bulk Density of Aggregate01:22

Bulk Density of Aggregate

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Bulk density refers to the mass of aggregate particles that would fill a unit volume. The concept of bulk density originates from the inability to pack aggregate particles in a manner that completely eliminates void spaces. Hence, the term bulk refers to the volume that encompasses both the aggregates and the voids. This measurement is crucial when aggregates are batched by volume and is used to convert quantities by mass to volume.
Most natural mineral aggregates, like sand and gravel,...
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Density and Archimedes' Principle01:05

Density and Archimedes' Principle

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When a lump of clay is dropped into water, it sinks. But if the same lump of clay is molded into the shape of a boat, it starts to float. Because of its shape, the clay boat displaces more water than the lump and experiences a greater buoyant force, even though its mass is the same. The same holds true for steel ships. The average density of an object majorly determines if the object will float. If an object's average density is less than that of the surrounding fluid, it will float. The...
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Quantification of Cellular Densities and Antigenic Properties using Magnetic Levitation
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マグネティック・レビテーションを用いた高通量密度測定

Shencheng Ge1, Yunzhe Wang1, Nicolas J Deshler1

  • 1Department of Chemistry & Chemical Biology , Harvard University , 12 Oxford Street , Cambridge , Massachusetts 02138 , United States.

Journal of the American Chemical Society
|June 12, 2018
PubMed
まとめ
この要約は機械生成です。

この研究は,細胞を含む様々な材料の密度測定のための高通量磁気浮揚 (MagLev) システムを提示します. 統合システムは96穴のプレートとスキャナーを使用して,効率的でラベルのない分析を行います.

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科学分野:

  • 分析化学
  • 生物化学
  • 材料科学

背景:

  • マグネティック・レビテーション (MagLev) は,密度ベースの分析を提供しますが,高通量機能はありません.
  • 現在のマグレフ・メソッドは複数のサンプルを同時に分析するのに最適化されていません.
  • 密度に基づく分類は様々な科学分野において極めて重要です.

研究 の 目的:

  • 密度測定のための統合された高通量分析システムを開発する.
  • 標準の96wellプレートとの互換性のためにMagLevテクノロジーを適応させる.
  • 生物細胞を含む様々な二磁性物質の密度ベースの分析を可能にします.

主な方法:

  • 磁場を再設計して 96穴のプレートで マグレフを起動させる
  • フラットベッドスキャナーとサンプルイメージングのための光学部品を組み込みました.
  • 磁気浮揚を活用して,様々な磁気質のサンプルを密度測定した.

主要な成果:

  • 統合されたマグレフシステムを用いて高通量密度測定を成功させた.
  • 生物学的 (ヒトの赤血球) と非生物学的サンプル (液体,固体,粉末,ビーズ) の両方でシステムの互換性を検証した.
  • 磁気浮揚によるラベルフリー密度分析を達成した.

結論:

  • 開発された統合MagLevシステムは,以前のスループット制限を克服します.
  • この技術は,材料の分析,分離,生化学研究における新しいアプリケーションを可能にします.
  • このシステムは,物質の普遍的な性質を用いた密度の特徴付けのためのシンプルな,ラベルフリーな方法を提供します.