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ヒトのロドプシンが阻害性Gタンパク質に結合する冷凍-EM構造

Yanyong Kang1, Oleg Kuybeda2, Parker W de Waal1

  • 1Center for Cancer and Cell Biology, Innovation and Integration Program, Van Andel Research Institute, Grand Rapids, MI, USA.

Nature
|June 15, 2018
PubMed
まとめ

Gタンパク質結合受容体は,特定の構造的相互作用によってGタンパク質またはアストリンを選択的に結合する. この研究は,活性化されたロドプシンが,分子レベルで抑制性Gタンパク質 (Gi) とどのように相互作用するかを明らかにしています.

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