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Updated: Feb 8, 2026

Co-Culture of Murine Small Intestine Epithelial Organoids with Innate Lymphoid Cells
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Co-Culture of Murine Small Intestine Epithelial Organoids with Innate Lymphoid Cells

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腸内皮質細胞のミトファギーは,腫瘍形成中に適応免疫を誘発する

Paul K Ziegler1, Julia Bollrath2, Charles K Pallangyo2

  • 1Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt am, Germany; Institute of Pathology, Frankfurt University Hospital, 60590 Frankfurt, Germany.

Cell
|June 19, 2018
PubMed
まとめ

細胞毒性の高いCD8+T細胞を持つ結腸直腸がんは,よりよい結果を示しています. 腸内皮質細胞はミトファジーとリソソーム損傷を利用して,腫瘍に対するT細胞の反応を高める.

キーワード:
ステート3適応免疫アンチゲン処理大腸がんクロスドレスリング腸内皮質細胞リンソーム膜の浸透ミトファジー

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