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アデノシン結合ヒトアデノシンA1受容体-Gi複合体の構造

Christopher J Draper-Joyce1, Maryam Khoshouei2,3, David M Thal1

  • 1Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.

Nature
|June 22, 2018
PubMed
まとめ

研究者はアデノシンとGi2タンパク質に結合するアデノシンA1受容体 (A1R) の活性構造を視覚化しました. これは,A1Rが特定のGタンパク質とどのように相互作用し,薬の開発を助けるのかについての重要な洞察を提供します.

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