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Updated: Feb 8, 2026

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フォスフォプロテオミクスによって解明された脳内GPCRシグナリング

Jeffrey J Liu1, Kirti Sharma1, Luca Zangrandi2

  • 1Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

Science (New York, N.Y.)
|June 23, 2018
PubMed
まとめ

研究者は,高通量フォスフォプロテオミクスを使用して,カッパオピオイド受容体 (KOR) のシグナリングを研究した. 彼らはmTOR経路を阻害することで KORに関連する副作用を減らし,同時に治療効果を維持することがわかった.

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