骨粗鬆症のスクリーニングで骨折を予防する:米国予防サービスタスクフォースの勧告声明
, Susan J Curry1, Alex H Krist2,3
1University of Iowa, Iowa City.
JAMA
|June 28, 2018
まとめ
骨粗鬆症のスクリーニングは,65歳以上の女性,およびリスクの高い更年期後の若い女性に対して推奨されます. 骨折を防ぐために男性をスクリーニングするには証拠が不十分です.
科学分野:
- ゲロントロジー
- 予防医学
- 骨 の 健康
背景:
- 骨粗鬆症は 50 歳以上の何百万人もの人に影響し 骨折,障害,死に至ります
- 骨粗鬆症の骨折,特に股関節骨折は,生活の質と独立性を著しく低下させます.
- 米国の人口の老化は 予防可能な骨粗鬆性骨折の 増加を予知しています
研究 の 目的:
- 骨粗鬆症のスクリーニングに関する最新の勧告を提供すること.
- 骨粗鬆性骨折のスクリーニング,リスク評価,治療の有効性に関する証拠をレビューする.
主な方法:
- 骨粗鬆性骨折のスクリーニングと治療に関する証拠の体系的なレビュー
- 前回の骨折や二次性骨粗鬆症の原因のない 閉経後の女性や高齢男性に焦点を当てた
- 骨の測定試験の精度と臨床リスク評価のツールの評価
主要な成果:
- 骨の測定検査は 骨粗鬆症を正確に検出し 女性と男性の骨折を予測します
- 臨床リスク評価ツールは骨粗鬆症のリスクを適度に特定します.
- 薬剤治療は閉経後の女性の骨折を効果的に軽減しますが,男性の証拠は不十分です.
結論:
- 骨の測定検査によるスクリーニングは,65歳以上の女性に対して推奨されます.
- リスク評価によって特定された,リスクが増加した65歳未満の閉経後の女性にはスクリーニングが推奨されます.
- 骨粗鬆症の骨折を予防するために男性にスクリーニングを推奨する証拠は不十分です.
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