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プラズモディアム・ビバックス (Plasmodium vivax) 侵入複合体の冷凍-EM構造

Jakub Gruszczyk1, Rick K Huang2, Li-Jin Chan1,3

  • 1The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Nature
|June 29, 2018
PubMed
まとめ

P. vivaxの網膜細胞結合タンパク質2b (PvRBP2b) とトランスファーリン受容体1 (TfR1) の相互作用を標的として,マラリア寄生虫の侵入を阻害する. 構造的な洞察は,ワクチン開発のための結合部位の保存を明らかにします.

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