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人間のシナプスGABAA受容体の構造

Shaotong Zhu1, Colleen M Noviello1, Jinfeng Teng1

  • 1Departments of Neuroscience and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Nature
|June 29, 2018
PubMed
まとめ

研究者は,脳の抑制に不可欠なヒトのα1β2γ2GABAA受容体を視覚化しました. これは,GABAとベンゾジアゼピンのような薬物がこの受容体にどのように影響し,治療開発に役立つかを理解するための構造的基礎を提供します.

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