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Updated: May 8, 2026

Adapting 3' Rapid Amplification of CDNA Ends to Map Transcripts in Cancer
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ヘリコースDed1pは,5' UTRにおける近縁の翻訳開始コドンの使用を制御する

Ulf-Peter Guenther1, David E Weinberg2,3,4, Meghan M Zubradt2,5

  • 1Center for RNA Science and Therapeutics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Nature
|June 29, 2018
PubMed
まとめ

DEAD-box RNAヘリケーズDed1p (およびその哺乳類のオートログDDX3) は,特にmRNA構造に対する反応として,近同類のスタートコドン使用を制御することによって,翻訳開始を調節する. このメカニズムは タンパク質の合成と 細胞のメオシスのようなプロセスに 極めて重要です

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