関連する実験動画

Updated: Feb 8, 2026

Caspase-3 Activity in the Rat Amygdala Measured by Spectrofluorometry After Myocardial Infarction
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Caspase-3 Activity in the Rat Amygdala Measured by Spectrofluorometry After Myocardial Infarction

Published on: January 12, 2016

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IL (インタールイキン) -10-STAT3-ガレクチン-3軸は,心筋梗塞後のオステオポントン産生マクロファージの修復性極化に不可欠である

Kohsuke Shirakawa1, Jin Endo1, Masaharu Kataoka1

  • 1Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (K.S., J.E., M.K., Y.K., N.Y., T.Y., S.I., H.M., S.G., H.K., T.H., K.F., M.S.).

Circulation
|July 4, 2018
PubMed
まとめ

オステオポントン (OPN) とガレクチン3は,心筋梗塞 (MI) の後のマクロファージの修復に不可欠です. IL-10-STAT3-ガレクチン-3経路は,これらの細胞のOPN生成を駆動し,線維症と破片の除去を通して心臓の修復を促進します.

キーワード:
ガレクチン-3心筋梗塞オステオポントン傷が治る

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