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Updated: Feb 8, 2026

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

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作者 訂正:炎症誘発IgA+細胞は,抗肝がん免疫を分解する

Shabnam Shalapour1, Xue-Jia Lin1,2, Ingmar N Bastian1

  • 1Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, California, 92093, USA.

Nature
|July 6, 2018
PubMed
まとめ

高脂肪食 (HFD) を摂取したマウスは,多数の変異を伴う肝細胞癌 (HCC) を発症した. この研究では,変異の種類を明らかにし,ヒトのHCCと比較し,がん研究を支援しています.

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