ATPase TRIP13による細胞サイクルチェックポイントタンパク質MAD2の再構築のメカニズム

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Updated: Feb 8, 2026

Evaluation of the Spindle Assembly Checkpoint Integrity in Mouse Oocytes
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Published on: September 13, 2022

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Claudio Alfieri1, Leifu Chang1,2, David Barford3

  • 1MRC Laboratory of Molecular Biology, Cambridge, UK.

Nature
|July 6, 2018
PubMed
まとめ

スピンドル・アセンブリ・チェックポイントは 細胞分裂を制御することで ゲノムの安定性を確保します この研究は,TRIP13とp31がミトスのチェックポイント複合体を分解し,適切な染色体分離のためのチェックポイントを無効化する方法を明らかにしています.

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