関連する実験動画

Updated: Feb 8, 2026

Quantifying Agonist Activity at G Protein-coupled Receptors
11:45

Quantifying Agonist Activity at G Protein-coupled Receptors

Published on: December 26, 2011

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Gタンパク質結合受容体アロステリーに関する構造的洞察

David M Thal1, Alisa Glukhova2, Patrick M Sexton2

  • 1Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia. david.thal@monash.edu.

Nature
|July 6, 2018
PubMed
まとめ

Gタンパク質結合受容体 (GPCR) は,アロステリックに作用する重要な細胞表面タンパク質である. 最近の構造研究は,GPCRアロステル変異の原子詳細を明らかにし,新しい治療開発の機会を提供している.

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