関連する実験動画
Updated: Feb 8, 2026

08:47
Super-resolution Imaging of the Bacterial Division Machinery
Published on: January 21, 2013
12.2K
光染料で装飾されたクリック可能なグラフェンナノリボンの超高解像度イメージング
Dharati Joshi1, Meghan Hauser1, Gregory Veber1
1Department of Chemistry , University of California , Berkeley , California 94720 , United States.
Journal of the American Chemical Society
|July 6, 2018
まとめ
原子的に正確なグラフェンナノリボン (GNR) は光タグで機能化されました. これにより,個々のGNRの高解像度イメージングが可能になり,電子機器への統合が進んでいます.
科学分野:
- 材料科学
- ナノテクノロジー
- 化学について
背景:
- 電子機器にグラフェンナノリボン (GNR) を組み込むことは,デバイスの製造サポートと互換性のある非破壊的高解像度イメージング技術がないため困難です.
- スキャニングプローブ顕微鏡 (SPM) と電子顕微鏡 (EM) のような既存の方法は,リトグラフィーと互換性のないサンプル準備を必要とします.
研究 の 目的:
- 個々のグラフェンナノリボン (GNRs) を高解像度でイメージングする方法を開発する.
- GNRを単一リボン電子デバイスアーキテクチャに機能的に統合できるようにする.
主な方法:
- 機能化のためのアジド群による超長コーブ型GNR (cGNR) の合成.
- cGNRのエッジにCy5光染料を付着させるための銅触媒のクリック化学.
- 染料で機能化されたcGNRのイメージングは,偏光限度および超解像度顕微鏡 (SRM) を使用します.
主要な成果:
- 成功して合成され,光で標識された超長cGNRs (~10μmまで).
- SRMは,40〜50nmの表面的なcGNR幅と10μmを超える長さを明らかにし,これまでのところ最も長いGNR画像です.
- 個々のcGNRは,稀な溶液中の堆積物と区別できる.
結論:
- 光学顕微鏡を用いた高解像度イメージングを可能にする.
- この技術は従来のイメージング方法の限界を克服し,GNRを電子機器に統合することを容易にする.
- 開発された方法は,個々の超長 GNR の可視化と特徴付けを可能にします.
関連する概念動画
Super-resolution Fluorescence Microscopy
14.6K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
14.6K
Chromatographic Resolution
2.2K
In chromatography, a solute moves through a chromatographic column and tends to spread, forming a Gaussian-shaped band. The longer the solute spends in the column, the broader the band becomes. The broadening can lead to overlaps within the column, affecting separation effectiveness.
The effectiveness of separation can be evaluated by determining the level of separation between two neighboring peaks in a chromatogram, which represents the individual components of a sample.
In chromatography,...
The effectiveness of separation can be evaluated by determining the level of separation between two neighboring peaks in a chromatogram, which represents the individual components of a sample.
In chromatography,...
2.2K
Racemic Mixtures and the Resolution of Enantiomers
21.8K
A racemic mixture, or racemate, is an equimolar mixture of enantiomers of a molecule that can be separated using their unique interaction with chiral molecules or media. Racemic mixtures are denoted by the (±)- prefix. This ‘optical rotation descriptor’ applies to the whole solution of a racemic mixture rather than a specific stereoisomer. Enantiomers typically have the same physical and chemical properties. Hence, they are not easily separable. However, enantiomers can exhibit...
21.8K
High-Resolution Mass Spectrometry (HRMS)
2.6K
The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the sum of the masses of protons and neutrons inside, considering the masses of protons and neutrons as equal. However, the masses of the proton (1.6726 × 10−24 g) and neutron (1.6749 × 10−24 g) are not truly equal. There is a minor error in the expression of atomic masses relative to the simplest atom of hydrogen. For...
2.6K
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
3.7K
The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the para...
3.7K
¹H NMR of Labile Protons: Temporal Resolution
1.7K
Protons bonded to heteroatoms such as nitrogen and oxygen exhibit a range of chemical shift values. This is due to the varying degree of hydrogen bonding between the proton and the heteroatom in other molecules. The extent of hydrogen bonding affects the electron density around the proton, thereby giving different chemical shift values for the protons in the proton NMR spectrum.
The –OH proton in alcohols typically appears in the range of δ 2 to 5 ppm but can vary depending on the specific...
The –OH proton in alcohols typically appears in the range of δ 2 to 5 ppm but can vary depending on the specific...
1.7K

