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関連する概念動画

From DNA to Protein03:06

From DNA to Protein

22.5K
The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
22.5K
Encoding01:19

Encoding

867
Information enters the brain through encoding, which is the input of information into the memory system. Once sensory information is received from the environment, the brain labels or codes it. The information is then organized with similar information and connected to existing concepts. Encoding occurs through automatic processing and effortful processing.
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
867
DNA-only Transposons02:57

DNA-only Transposons

17.5K
DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...
17.5K
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

16.7K
For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
16.7K
Proteins: From Genes to Degradation02:11

Proteins: From Genes to Degradation

14.5K
Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This is referred to as “The Central Dogma of Molecular Biology” - a term coined by Francis Crick.  Central dogma is a firm principle in biology that defines the flow of genetic information within any life form. The two fundamental steps in central dogma are - transcription and translation.
Transcription is the synthesis of RNA...
14.5K
DNA Helicases00:55

DNA Helicases

24.2K
DNA unwinding helicase enzymes are a type of motor protein. Motor proteins can translocate along filaments or polymers using energy generated from ATP hydrolysis. Helicases are involved in all the important cellular processes where DNA unwinding is required, such as DNA replication, repair, recombination, and transcription. They are present in all living organisms, but vary in their structure, function, and mechanism of action. For example, in prokaryotes, DnaB helicase binds and translocates...
24.2K

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関連する実験動画

Updated: Feb 8, 2026

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles
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Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles

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DNAでコードされたタンパク質 ジャヌスナノ粒子

Oliver G Hayes, Janet R McMillan, Byeongdu Lee1

  • 1X-ray Science Division , Argonne National Laboratory , Argonne , Illinois 60439 , United States.

Journal of the American Chemical Society
|July 11, 2018
PubMed
まとめ

研究者はDNA結合を用いて タンパク質ベースのジャヌスナノ粒子を作りました これらの新しいナノ粒子は 独自の3D超格子に自己組み立てられ 調節可能なコロイド結晶構造を可能にします

科学分野:

  • バイオテクノロジー
  • 材料科学
  • ナノテクノロジー

背景:

  • ジャヌス粒子は非対称な機能により ユニークな性質を備えています
  • これらの非中心対称粒子を合成することは 重要な課題です
  • タンパク質とDNAは ナノスケールエンジニアリングの 汎用性のあるプラットフォームを提供します

研究 の 目的:

  • 新しいタンパク質ベースの ジャヌスナノ粒子を合成する
  • このナノ粒子が自己組織化して 3次元超グリッドに 組み合わされる様子を調査します
  • コロイド結晶化のためのDNA媒介の相互作用の調整性を実証する.

主な方法:

  • タンパク質の化学的アニソトロピーとDNAの化学をナノ粒子合成に利用する.
  • 配列特異な核酸ドメインでタンパク質をコードする.
  • オリゴヌクレオチド配列を分子間DNA結合に利用する.
  • 六角層構造のスーパーグリッドの自己組み立てを研究しています

主要な成果:

  • タンパク質ベースのジャヌスナノ粒子の合成に成功
  • 先例のない多元ナノ粒子超グリッドの形成

さらに関連する動画

Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis
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Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis

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Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
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Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

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関連する実験動画

Last Updated: Feb 8, 2026

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles
13:09

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles

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Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis
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Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis

Published on: July 16, 2020

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Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability
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Synthesis of PolyN-isopropylacrylamide Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Published on: February 27, 2016

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  • DNA結合の調節による調節可能な格子拡大の実証.
  • ユニークな低対称性六角層構造の実現
  • 結論:

    • タンパク質ベースのジャヌスナノ粒子は, 設計されたコロイド結晶の効果的な構成要素です.
    • DNAでコードされたナノ粒子は 先進的な材料の設計に 多用途のプラットフォームを提供します
    • このアプローチは,コロイド結晶化とナノテクノロジーの応用のための先例を確立しています.