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Updated: Feb 7, 2026

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ヒスティジン分解はメトトレキサート感受性の主要な決定因子である

Naama Kanarek1,2,3,4, Heather R Keys1, Jason R Cantor1,2,3,4

  • 1Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Department of Biology, Cambridge, MA, USA.

Nature
|July 12, 2018
PubMed
まとめ

ヒスティジンの分解経路はメトトレキサートに対する癌細胞の感受性に影響する. この経路の強化は,食事によるヒスティジンによる可能性があり,化学療法の有効性と患者の生存率を向上させる可能性があります.

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