関連する実験動画

Updated: Feb 7, 2026

Construction of Model Lipid Membranes Incorporating G-protein Coupled Receptors GPCRs
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Construction of Model Lipid Membranes Incorporating G-protein Coupled Receptors GPCRs

Published on: February 5, 2022

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PtdIns ((4,5) P2はGPCRの活性状態を安定させ,Gタンパク質結合の選択性を高める

Hsin-Yung Yen1,2, Kin Kuan Hoi1, Idlir Liko1,2

  • 1Chemical Research Laboratory, University of Oxford, Oxford, UK.

Nature
|July 12, 2018
PubMed
まとめ

Phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5) P2) は,Gタンパク質結合受容体 (GPCRs) とそのGタンパク質パートナーに特異的に結合し,受容体-Gタンパク質結合を強化し,薬物標的化のための新しい経路を提供します.

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