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Updated: Feb 7, 2026

In Vivo Direct Reprogramming of Resident Glial Cells into Interneurons by Intracerebral Injection of Viral Vectors
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非ウイルスゲノム標的化によるヒトT細胞機能と特異性の再プログラム

Theodore L Roth1,2,3,4,5, Cristina Puig-Saus6, Ruby Yu3,4,5

  • 1Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA, USA.

Nature
|July 12, 2018
PubMed
まとめ

この研究では,非ウイルス性CRISPR-Cas9ゲノム編集システムを導入し,T細胞を再プログラムします. この方法は,自己免疫疾患の矯正や癌の免疫療法を含む治療用途のための正確な大規模なDNA挿入を可能にします.

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