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Updated: May 11, 2026

Focus Formation: A Cell-based Assay to Determine the Oncogenic Potential of a Gene
08:18

Focus Formation: A Cell-based Assay to Determine the Oncogenic Potential of a Gene

Published on: December 31, 2014

Mxタンパク質:クローンされたMxcDNAで変換された3T3細胞における構成的発現は,インフルエンザウイルスに対する選択的耐性を授与する

P Staeheli, O Haller, W Boll

    Cell
    |January 17, 1986
    PubMed
    まとめ

    インフルエンザウイルスに耐性のあるマウスは,インターフェロン (IFN) によって誘発されるMxタンパク質を持っています. このタンパク質は,他のIFN効果とは独立して,オートマイキソウイルスに対する特定の耐性を授与します.

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    Co-immunoprecipitation of the Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein09:39

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    Leaky Scanning02:28

    Leaky Scanning

    During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...