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Updated: Feb 7, 2026

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
09:46

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores

Published on: August 19, 2013

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自由カルボキシル酸のリガンド活性化β-C ((sp3) -Hオレフィネーション

Zhe Zhuang1, Chang-Bin Yu1, Gang Chen1

  • 1Department of Chemistry , The Scripps Research Institute , 10550 North Torrey Pines Road , La Jolla , California 92037 , United States.

Journal of the American Chemical Society
|July 22, 2018
PubMed
まとめ

研究者は新しいリガンドを用いたC ((sp3) -H活性化のための新しい方法を開発した. このパラジアム触媒反応は,自由カルボキシル酸のオレフィネーションを可能にし,従来のヘック結合の代替品を提供します.

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Acidity of Carboxylic Acids01:21

Acidity of Carboxylic Acids

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Carboxylic acids are the strongest among organic acids, as they readily lose the hydroxyl proton to form a resonance-stabilized carboxylate ion. In comparison, the acid derivatives lack acidic hydrogens directly attached to a functional group. In these compounds, the acidic nature arises from their ability to lose α hydrogens, making them weakly acidic.
The relative acidic strength of the derivatives can be explained based on the extent of resonance stabilization of the conjugate base. The...
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