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Updated: Feb 7, 2026

Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity
08:00

Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity

Published on: July 10, 2019

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フォスフォディエステラーゼ1型阻害による急性心機能改善

Toru Hashimoto1, Grace E Kim1, Richard S Tunin1

  • 1Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (T.H., G.E.K., R.S.T., T.A., S.H., R.N., G.Z., D.I.L., D.A.K.).

Circulation
|July 22, 2018
PubMed
まとめ

ITI-214によるPDE1抑制は,哺乳類の心臓機能と血管の拡張を改善する. PDE1Cを発現する種に特に有効なこの新しい治療法は,心不全の治療に有望である.

キーワード:
アデノシンアドレナージックβ抗体カルシウム周期的なAMPサイクルヌクレオチド・フォスフォディエステラーゼ1型心不全

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Isolation of Functional Cardiac Immune Cells

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In vitro Assessment of Cardiac Reprogramming by Measuring Cardiac Specific Calcium Flux with a GCaMP3 Reporter05:04

In vitro Assessment of Cardiac Reprogramming by Measuring Cardiac Specific Calcium Flux with a GCaMP3 Reporter

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