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Updated: Feb 7, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
06:48

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ゲノムの特徴と転移性前立腺がんの構造的変化

David A Quigley1, Ha X Dang2, Shuang G Zhao3

  • 1Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, CA, USA; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, USA.

Cell
|July 24, 2018
PubMed
まとめ

転移性前立腺がんの全ゲノム構造変異は 疾患の進行を促す新たな要因を明らかにしています これらの中には,アンドロゲン受容体 (AR) 近くの増強物質と,特定の変異体とDNA修復欠陥との間のリンクが含まれます.

キーワード:
BRCA2 についてアンドロゲン受容体カストレーションに抵抗する前立腺がんクロモトリプシス遺伝子融合ゲノム学転移する構造的な変化タンドム複製全ゲノムシーケンシング

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