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Updated: Feb 7, 2026

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay

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サイクリン依存キナーゼ12は,内臓リーシュマニアの薬標的である

Susan Wyllie1, Michael Thomas1, Stephen Patterson1

  • 1Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK.

Nature
|July 27, 2018
PubMed
まとめ

CRK12を標的とした新しい抗リーシュマニア薬が有望です ピラゾロピリミジンベースの化合物は,臨床前モデルで有効であり,内臓リーシュマニアの新たな治療法を提供している.

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