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Updated: Apr 3, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

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高または低GTPase活性を持つRas p21タンパク質は,NIH/3T3細胞を効率的に変換することができます

J C Lacal, S K Srivastava, P S Anderson

    Cell
    |February 28, 1986
    PubMed
    まとめ

    Ras p21変異体は,GTPaseの活性が低下することなく,変異特性を獲得することができます. この研究は,RASの腫瘍遺伝子の活性化に関する以前の仮定に異議を唱え,代替メカニズムを通じて効率的な変換が起こり得ることを示しています.

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