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Updated: Feb 3, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

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C ((sp3) に富んだ複雑性を,サイクル加法とC-Cクロスカップリング反応を組み合わせることで構築する

Tie-Gen Chen1, Lisa M Barton1, Yutong Lin1

  • 1Department of Chemistry, The Scripps Research Institute (TSRI), La Jolla, CA, USA.

Nature
|August 1, 2018
PubMed
まとめ

この研究は,サイクル添加と炭素対炭素のクロスカップリング反応を組み合わせた新しい合成戦略を導入しています. このアプローチにより,薬剤発見のための複雑な分子の効率的,モジュラー,およびエナチオセレクティブの合成が可能になります.

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