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Updated: Feb 7, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

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CRISPRで誘導されるDNAポリメラーゼは,調整可能なウィンドウですべてのヌクレオチドの多様化を可能にします

Shakked O Halperin1,2,3, Connor J Tou1, Eric B Wong1

  • 1Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.

Nature
|August 3, 2018
PubMed
まとめ

研究者はEvolvRという 継続的な遺伝子コードの多様化システムを開発しました このCRISPRによる DNAポリメラーゼツールは 生物工学のための 急速なゲノム編集と 新しい特性の発見を可能にします

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DNA Polymerase Activity Assay Using Near-infrared Fluorescent Labeled DNA Visualized by Acrylamide Gel Electrophoresis07:38

DNA Polymerase Activity Assay Using Near-infrared Fluorescent Labeled DNA Visualized by Acrylamide Gel Electrophoresis

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Unlike eukaryotes, bacteria use a single RNA Polymerase (RNAP) to transcribe all genes. The different subunits of bacterial RNAPhave distinct functions. The multisubunit structure of the bacterial RNAP helps the enzyme to maintain catalytic function, facilitate assembly, interact with DNA and RNA, and self-regulate its activity.
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