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Updated: Feb 7, 2026

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
11:17

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

Published on: February 10, 2014

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ポックスウイルスは,mTORC1-mTORC2 調節回路の障害によって細胞検出を回避する

Nathan Meade1, Colleen Furey1, Hua Li1

  • 1Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Cell
|August 7, 2018
PubMed
まとめ

ポックスウイルスはF17タンパク質を用いて細胞のmTOR信号伝達を妨害し,抗ウイルス反応を阻害する. この保存されたウイルスの戦略は,ウイルスのDNAの重要なセンサーであるcGASを劣化させ,宿主の防御を標的とする.

キーワード:
スティングcGAS について生まれつきの免疫インターフェロンmTOR についてポックスウイルスタンパク質合成センサー

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