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哺乳類のミトコンドリア変換開始のユニークな特徴は,冷凍-EMによって明らかになった

Eva Kummer1, Marc Leibundgut1, Oliver Rackham2

  • 1Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Zurich, Switzerland.

Nature
|August 10, 2018
PubMed
まとめ

ミトコンドリアトランスレーション開始は,リーダーレスmRNAと形式化されたイニシアターtRNAを結合する追加のドメインを持つユニークなイニシアーション因子2 (mtIF2) を使用します. この構造は,ミトコンドリアのタンパク質合成が,イニシアチブファクター1なしでどのように開始されるかを明らかにする.

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