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Updated: Feb 6, 2026

Isolation of CA1 Nuclear Enriched Fractions from Hippocampal Slices to Study Activity-dependent Nuclear Import of Synapto-nuclear Messenger Proteins
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Isolation of CA1 Nuclear Enriched Fractions from Hippocampal Slices to Study Activity-dependent Nuclear Import of Synapto-nuclear Messenger Proteins

Published on: August 10, 2014

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核孔はPOM121駆動のE2F1,MYC,AR核輸入を増やすことで致死性前立腺がんを促進する

Veronica Rodriguez-Bravo1, Raffaella Pippa1, Won-Min Song2

  • 1Cancer Biology Department, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Medical Oncology Department, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Pathology Department, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Cell
|August 14, 2018
PubMed
まとめ

核毛孔複合体 (NPC) は細胞輸送を調節しますが,その癌の役割は不明です. 前立腺がん (PC) の重要なNPCタンパク質であるPOM121をターゲットにすることで,腫瘍の成長を抑制し,生存率を向上させます.

キーワード:
E2F1 についてGATA2 についてMYC についてPOM121 についてアンドロゲン受容体輸入する β核の輸入核孔原子力輸送前立腺がん

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