ポリプロイド小麦の転写風景

R H Ramírez-González, P Borrill, D Lang

Science (New York, N.Y.)

|August 18, 2018

まとめ

パンの小麦では,ホモエオログの遺伝子発現は組織によって変化し,多くの遺伝子は偏った発現を示している. この変異は,特に高再結合領域では,遺伝子機能の進化と作物特性の発達に関する洞察を提供します.

科学分野:

ゲノミクス
植物生物学
農作物科学

背景:

パン小麦のようなポリプロイド種は,重要な現象型のための協調された同質遺伝子発現に依存しています.
ホモエオログの表現を理解することは,作物の大きな改善に不可欠です.

研究の目的:

ヘクサプロイドパンの小麦のホモエオログ表現パターンの包括的な全ゲノム分析を行う.
小麦の組織と品種間の表現バイアスと非対称性のパターンを特定する.

主な方法:

広範な遺伝子発現データセットの統合
ホモエオログ表現パターンの全ゲノム分析
共同表現ネットワークの構築と詳細な表現アトラス

主要な成果:

小麦のホメオログの約30%はバランスのとれない表現を示し,組織によって有意に変化します.
表現不対称性は,高再結合の遠隔染色体領域で顕著であり,組織間,カルティバル間,およびコード配列の変化を示しています.
同発現ネットワークは,ホモエオログの広範な発達調整を示しています.

結論:

これらの領域の転写的にダイナミックな遺伝子は,ネオまたはサブ機能化の初期段階を示す可能性があります.
この研究は,小麦の農学的な特徴に関連する候補遺伝子をターゲットにするための枠組みを提供します.
ホモエオログ表現バイアスを理解することは,作物育種のためのポリプロイディを活用する鍵です.

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