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Updated: Feb 6, 2026

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Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
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トラウマ性脳損傷 と 自殺 リスク の 関連
Trine Madsen1,2, Annette Erlangsen1,3,4,5, Sonja Orlovska2
1Danish Research Institute of Suicide Prevention, Mental Health Centre Copenhagen, Capital Region of Denmark, Copenhagen, Denmark.
JAMA
|August 19, 2018
まとめ
トラウマ性脳損傷 (TBI) がある人は自殺のリスクがかなり高くなります このリスクは,特に怪我の直後に,TBIの重度と頻度によって増加します.
科学分野:
- 神経科学
- 公衆衛生
- 流行病学
背景:
- トラウマ性脳損傷 (TBI) は長期的な精神的影響と関連しています.
- TBIと自殺リスクとの関連は 更に調査が必要です
研究 の 目的:
- トラウマ性脳損傷 (TBI) と 自殺のリスクとの関連を調査する.
主な方法:
- 1980年から2014年にかけてのデンマーク全国のレジスタリを用いた後回顧的なコホート研究.
- 740万人以上 (≥10歳) が含まれており,567,823人がTBIのために医師に接触しました.
- プアソン回帰では 自殺リスクを分析し 骨折や精神疾患の診断や 自傷行為などの 共同変数を調整しました
主要な成果:
- TBI の患者では,TBI の患者と比べて自殺率がほぼ2倍 (IRR 1.90) でした.
- 重度のTBIは自殺リスクが最も高かった (IRR2. 38).
- 自殺のリスクはTBIの接触者数に伴い増加し,負傷後6ヶ月以内に最も高かった (IRR3.67).
結論:
- TBIの医師との接触は 自殺リスクの上昇と関連しています
- リスクは,TBIの重度と医師との接触の頻度に依存します.
- TBIの診断に 近いところでは 自殺のリスクが 大きく上昇します
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