関連する実験動画

Updated: Feb 6, 2026

Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR
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Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR

Published on: July 27, 2019

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TUT4/7による尿化がヒトLINE-1の逆転移を制限する

Zbigniew Warkocki1, Paweł S Krawczyk2, Dorota Adamska2

  • 1Laboratory of RNA Biology and Functional Genomics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.

Cell
|August 21, 2018
PubMed
まとめ

LINE-1の逆転移は,LINE-1mRNAに尿素を加えることで制御される. このTUT4およびTUT7酵素による尿解は,LINE-1の活動を制限し,ゲノムの安定性を維持します.

キーワード:
3′RACE-seq についてL1-ORF1pL1-ORF2pライン-1MOV10 についてTUT4 についてTUT7 についてポリエステルリトロトランスポジションウリジレーション

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