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トリフェニルメタン染料をAβから派生したトリマーに結合させるための再利用

Patrick J Salveson1, Sepehr Haerianardakani1, Alexander Thuy-Boun1

  • 1Department of Chemistry , University of California Irvine , Irvine , California 92697-2025 , United States.

Journal of the American Chemical Society
|August 21, 2018
PubMed
まとめ

結晶紫色および類似の染料は,アルツハイマー病に関連するアミロイドβ (Aβ) オリゴーマーと結合する. この結合は,構造研究によって詳細に示され,染料がAβトリマーとどのように相互作用し,アルツハイマー病の将来の薬剤発見を導きます.

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