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The DNA Helix01:16

The DNA Helix

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Overview
157.6K
The DNA Helix01:07

The DNA Helix

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Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
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Chirality02:25

Chirality

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Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
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DNA Replication02:40

DNA Replication

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DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied.  After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
Replication in Prokaryotes
DNA replication...
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Chirality in Nature02:30

Chirality in Nature

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Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
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DNA Topoisomerases02:02

DNA Topoisomerases

35.7K
Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types. ...
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Updated: Feb 6, 2026

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
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スイッチ可能なキラリティを持つDNA誘導プラズモニックヘリックス

Xiang Lan, Tianji Liu1,2, Zhiming Wang1

  • 1Institute of Fundamental and Frontier Sciences , University of Electronic Science and Technology of China , Chengdu 610054 , China.

Journal of the American Chemical Society
|August 22, 2018
PubMed
まとめ
この要約は機械生成です。

研究者はDNAオリガミを用いて 金ナノロッドのキラル構造を動的に制御した. これはキラル光学特性のアクティブスイッチングを可能にし,高度な再構成可能なキラル材料への道を切り開きます.

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関連する実験動画

Last Updated: Feb 6, 2026

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科学分野:

  • ナノテクノロジー
  • 材料科学
  • 超分子化学

背景:

  • ナノ粒子の自己組み立て構造を動的に調整することは 先進的な材料にとって極めて重要です
  • キラルナノ粒子の上部構造とその光学特性を制御することは依然として大きな課題です.

研究 の 目的:

  • 金ナノロッド3Dキラルプラズモニック・スーパーストラクチャの ダイナミック・コントロールを証明する
  • 上部構造の幾何学を再構成することによって,キラル光学特性を積極的に切り替える.

主な方法:

  • 金ナノロッドの組み立てのテンプレートとしてDNAオリガミの超分子ポリマーを使用した.
  • DNAテンプレート構造を再構成するためにDNA-ヒモホールド媒介の構成変化を使用した.
  • チラルプラズモニック特性の変化を調査した.

主要な成果:

  • ゴールドナノロッドの 階段ヘリクスの上部構造を 制御した
  • 折りたたまれた状態と伸ばされた状態,そして反対のキラルハンド性との間の再構成を達成しました.
  • 円形の二重化振幅,ピーク周波数,およびキラリティのシグネチャーのアクティブスイッチングが実証された.

結論:

  • DNAによる戦略により,キラルプラズモンの上部構造を動的に制御できます.
  • このアプローチは,活性光制御のための再構成可能なキラル材料の開発を容易にする.
  • 合理的な分子設計と 予測可能な自己組み立てが これらの材料の進歩の鍵です