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Updated: Feb 6, 2026

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
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Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy

Published on: May 26, 2023

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パルキンとPINK1はSTING誘発の炎症を和らげる

Danielle A Sliter1, Jennifer Martinez2, Ling Hao1

  • 1Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

Nature
|August 24, 2018
PubMed
まとめ

パーキンソン病の遺伝子であるPINK1とパーキンは 通常 損傷したミトコンドリアを浄化します ミトファギーは先天的な免疫を制御する役割を明らかにし,STINGを遮断することによって,炎症とニューロンの損失を引き起こす.

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