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Updated: Feb 6, 2026

Multi-parameter Measurement of the Permeability Transition Pore Opening in Isolated Mouse Heart Mitochondria
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Multi-parameter Measurement of the Permeability Transition Pore Opening in Isolated Mouse Heart Mitochondria

Published on: September 7, 2012

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LC-MS/MS プロテオフォームプロファイリングは,ミトコンドリアにおけるシトクロームcペロキシダースの自己酸化と,そのヘムから機能的に重要な穴のホッピングを暴露する

Meena Kathiresan1, Ann M English1

  • 1Quebec Network for Research on Protein Function, Structure and Engineering (PROTEO), and Department of Chemistry and Biochemistry , Concordia University , Montreal , QC H4B 1R6 , Canada.

Journal of the American Chemical Society
|August 28, 2018
PubMed
まとめ

シトクロームc過酸化酵素 (Ccp1) プロテオフォームは,新しい機能と基板結合部位を明らかにし,根幹移転によって酸化される. このプロセスは,特にヘムラビライゼーションは,Ccp1を拡張します.

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