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Updated: Feb 6, 2026

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data
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広範囲にわたる内部ポリアデニレーションは,白血病における腫瘍抑制遺伝子を無効化する

Shih-Han Lee1, Irtisha Singh2,3, Sarah Tisdale1

  • 1Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|August 29, 2018
PubMed
まとめ

異常なメッセンジャーRNA (mRNA) 処理,特に内性ポリアデニレーションは,慢性リンパ球性白血病 (CLL) の腫瘍抑制遺伝子を無効化する. このmRNA現象は 癌の進行を促す遺伝的変異よりも一般的です

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