関連する実験動画

Updated: May 5, 2026

Isolation of Soluble and Insoluble PrP Oligomers in the Normal Human Brain
11:29

Isolation of Soluble and Insoluble PrP Oligomers in the Normal Human Brain

Published on: October 3, 2012

10.3K

プリオンタンパク質とスクレイピの潜伏時間遺伝子の結合

G A Carlson, D T Kingsbury, P A Goodman

    Cell
    |August 15, 1986
    PubMed
    まとめ

    単一の遺伝子であるPrn-iは,マウスのスクレイピープリオン病の潜伏期を制御する. この遺伝子は,この遺伝子です.

    さらに関連する動画

    Protein Misfolding Cyclic Amplification of Prions10:12

    Protein Misfolding Cyclic Amplification of Prions

    Published on: November 7, 2012

    18.8K
    Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans12:57

    Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

    Published on: January 8, 2015

    15.7K

    関連する概念動画

    Amyloid Fibrils03:03

    Amyloid Fibrils

    Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
    Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
    10.3K
    Leaky Scanning02:28

    Leaky Scanning

    During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
    4.5K
    Subviral Agents01:29

    Subviral Agents

    Subviral agents are infectious entities that resemble viruses but lack one or more viral components, such as a capsid or essential replication machinery. These agents include viroids, prions, and satellites, each possessing distinct structural and functional characteristics that influence their mode of infection and replication.Viroids are the simplest subviral agents, consisting of circular, single-stranded RNA molecules without a protein coat. They exclusively infect plants, relying entirely...
    940