ポリマーのキラル対キラル通信:ヘリカルセンスとキラリティの両方を周辺で制御するためのユニークなアプローチ

Katherine Cobos¹, Emilio Quiñoá¹, Ricardo Riguera¹

¹Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS) and Departamento de Química Orgánica , Universidade de Santiago de Compostela , E-15782 Santiago de Compostela , Spain.

Journal of the American Chemical Society

|August 30, 2018

まとめ

研究者はヘリキュール型ポリマーに新しいキラルな"軍曹と兵士"効果を開発した. この方法は,ポリマーのキラリティを制御し,様々なキラルのペンダントグループで装飾された単手ヘリクスの作成を可能にする.

科学分野:

ポリマー化学
キラリティ
超分子化学

背景:

クラシックな"軍曹と兵士"効果は,ポリマーの螺旋性誘導のための確立された方法です.
ポリマーの螺旋感覚と外部キラリティの両方を制御することは,材料科学における重要な課題です.

研究の目的:

ポリマーのヘリカルと外部のヒラリティを制御するために,ヒラルのサージェントとヒラルのソルジャーを使用する新しいアプローチを導入します.
主要なコンポーネントのキラリティに関係なく,特定の螺旋感覚 (MまたはP) を誘導する能力を実証する.

主な方法:

キラルペンダントグループ ("キラルソルジャー") とキラルマイナーコンポーネント ("キラルサージェント") を含む共ポリマーの合成.
軍曹と兵士の絶対的な構成と,その結果生じるポリマーの螺旋的な感覚との関係を調べる.
構成安定化によるキラル対キラル通信の分析.

主要な成果:

同じ螺旋感覚 (Pヘリックス) は,キラル・ソルジャントの単一のエナンティオマーとペアリングされたとき,キラル・ソルジャントの異なるエナンティオマーから誘導された.
ポリマーの螺旋的な感覚は軍曹の構成にのみ依存していることが分かりました兵士の構成ではないのです
ヘリスはエナティオメアまたはキラル・ソルジャーのラセミック混合物で装飾され,多用途性を示します.

結論:

この新しいキラルサージントとソルジャーのアプローチは,ポリマーの螺旋と外部のキラル性を正確に制御します.
この方法は,調整可能な外周キラリティを持つ単手ヘリクを準備することを可能にし,先進的な材料のための新しい可能性を提供します.

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