関連する実験動画

Updated: Aug 6, 2026

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments
09:14

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments

Published on: January 27, 2016

哺乳類のゲノムDNAの長距離制限サイトマッピング

W R Brown, A P Bird

    Nature
    |July 6, 1986
    PubMed
    まとめ

    研究者らはパルスフィールドゲル電泳を用いてマウスのゲノムDNAをマッピングした. めったに発生しない切断制限酵素の部位が群集していることが判明し,ゲノム内の遺伝子に富んだ領域を潜在的に示す可能性がある.

    さらに関連する動画

    CAPRRESI: Chimera Assembly by Plasmid Recovery and Restriction Enzyme Site Insertion07:37

    CAPRRESI: Chimera Assembly by Plasmid Recovery and Restriction Enzyme Site Insertion

    Published on: June 25, 2017

    Mapping Mammalian 3D Genome Interactions with Micro-C-XL11:41

    Mapping Mammalian 3D Genome Interactions with Micro-C-XL

    Published on: November 3, 2023

    関連する概念動画

    Genomic DNA in Eukaryotes00:58

    Genomic DNA in Eukaryotes

    Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
    Restriction Enzymes01:11

    Restriction Enzymes

    Restriction enzymes are bacterial enzymes used to cut DNA in a sequence-specific manner. To cleave DNA, they bind to specific palindromic sequences called restriction sites. Such palindromic DNA sequences or inverted repeats are commonly found in regions of functional significance, such as the origin of replication, gene operator sites, and regions containing transcription termination signals.
    The host bacteria protect their own genomic DNA from these enzymes by methylating these sites. Some...