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Updated: Feb 5, 2026

Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries
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Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries

Published on: September 6, 2012

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NEMO-IκBキナーゼ相互作用に対する細胞浸透性バイサイクルペプチジル阻害剤

Curran A Rhodes1, Patrick G Dougherty1, Jahan K Cooper1

  • 1Department of Chemistry and Biochemistry , The Ohio State University , 100 West 18th Avenue , Columbus , Ohio 43210 , United States.

Journal of the American Chemical Society
|September 4, 2018
PubMed
まとめ

研究者は細胞内タンパク質を標的とする 細胞に浸透するバイサイクルペプチドを開発しました これらのペプチドは,NEMO- IKKβの相互作用を成功裏に抑制し,抗炎症薬および抗癌薬として潜在性を示した.

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