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関連する概念動画

Pancreatic Juice and Secretion01:26

Pancreatic Juice and Secretion

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Pancreatic juice is a clear fluid produced by the pancreas, containing water, salts, sodium bicarbonate, and enzymes vital for digestion in the small intestine. It helps break down large molecules, facilitating nutrient absorption.
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
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Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.3K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

745
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
373
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

877
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
877
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion01:27

Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

2.6K
The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
Insulin and C-peptide are...
2.6K
このページは機械翻訳されています。他のページは英語で表示される場合があります。View in English
  1. ホーム
  2. 研究分野
  3. 生物医学と臨床科学
  4. 腫瘍学とがん発生
  5. 予測・予測マーカー
  6. 前がん性腫瘍細胞は,管系を通過することができます.
  1. ホーム
  2. 研究分野
  3. 生物医学と臨床科学
  4. 腫瘍学とがん発生
  5. 予測・予測マーカー
  6. 前がん性腫瘍細胞は,管系を通過することができます.

関連する実験動画

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line
06:24

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Published on: April 11, 2025

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前がん性腫瘍細胞は,管系を通過することができます.

Alvin P Makohon-Moore1, Karen Matsukuma2, Ming Zhang3

  • 1The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|September 5, 2018

PubMed で要約を見る

まとめ
この要約は機械生成です。

臓がんの進行には,長年にわたって進化する前身の病変が含まれます. 遺伝子分析では 一つの臓の 独特な病変は 管道系に侵入した 単一の腫瘍に起因します

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Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets
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Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

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Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma
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Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

Published on: November 19, 2019

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関連する実験動画

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line
06:24

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Published on: April 11, 2025

940
Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets
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Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

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Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma
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Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

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科学分野:

  • 腫瘍学
  • 遺伝学
  • 進化生物学

背景:

  • 大人のがんのほとんどは 非侵襲的な前駆体病変から生じる.
  • 併存した病変の進化的・遺伝的関連は 十分に理解されていない.

研究 の 目的:

  • 同じ臓内の臓がんとその前身の病変の進化的および遺伝的関係を調査する.
  • 臓がんの段階的な進行モデルを再考する

主な方法:

  • 臓がんの体内変異と,特定の臓部位からの前駆体病変の分析
  • 病変の進化的関係を推論する.

主要な成果:

  • 祖先の細胞が 複製して広がり 複数の病変を 生み出したことを確認しました
  • その後 駆動遺伝子の変異により 侵襲的な臓がんが長年にわたって発生しました
  • 単一の臓の 明確な高度の前駆体損傷は しばしば単一の腫瘍を代表し 管道系を植民地化しています

結論:

  • 臓がんは長期間,多段階の進行を経て発症する.
  • 一つの臓内の独立した前駆体病変は,共通の腫瘍源から発生する可能性があります.
  • この研究は 臓がんの進化と空間的遺伝的差異の理解を 再構築するものです