Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Bond Energies and Bond Lengths02:49

Bond Energies and Bond Lengths

31.5K
Stable molecules exist because covalent bonds hold the atoms together. The strength of a covalent bond is measured by the energy required to break it, that is, the energy necessary to separate the bonded atoms. Separating any pair of bonded atoms requires energy — the stronger a bond, the greater the energy required to break it.
31.5K
Peptide Bonds02:43

Peptide Bonds

83.2K
A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
83.2K
Bonding in Metals02:32

Bonding in Metals

52.5K
Metallic bonds are formed between two metal atoms. A simplified model to describe metallic bonding has been developed by Paul Drüde called the “Electron Sea Model”. 
52.5K
Ionic Bonds00:42

Ionic Bonds

131.1K
Overview
When atoms gain or lose electrons to achieve a more stable electron configuration they form ions. Ionic bonds are electrostatic attractions between ions with opposite charges. Ionic compounds are rigid and brittle when solid and may dissociate into their constituent ions in water. Covalent compounds, by contrast, remain intact unless a chemical reaction breaks them.
Opposing Charges Hold Ions Together in Ionic Compounds
Ionic bonds are reversible electrostatic interactions between ions...
131.1K
Valence Bond Theory02:45

Valence Bond Theory

50.3K
Overview of Valence Bond Theory
50.3K
Valence Bond Theory02:42

Valence Bond Theory

11.3K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
11.3K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Active Templating by Mechanochemistry.

Organic letters·2026
Same author

Sequence-Dependent Folding of Recognition-Encoded Melamine Oligomers.

Journal of the American Chemical Society·2026
Same author

Negative cooperativity in the formation of two H-bonds with an oxygen H-bond acceptor.

Chemical science·2026
Same author

Prediction of Protein-Ligand Binding Affinities Using Atomic Surface Site Interaction Points.

Journal of chemical information and modeling·2026
Same author

Template-directed ligation of recognition-encoded melamine oligomers.

Chemical science·2025
Same author

Supramolecular assembly properties of a mixed-sequence recognition-encoded melamine oligomer.

Organic & biomolecular chemistry·2025

関連する実験動画

Updated: Feb 5, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

10.4K

フェニラセチレンバックボーンを基にしたH結合のデュプレックス

Jonathan A Swain1, Giulia Iadevaia1, Christopher A Hunter1

  • 1Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.

Journal of the American Chemical Society
|September 5, 2018
PubMed
まとめ

フェニラセチレンオリゴーマーにはフェノールとフォスフィン酸化物群があり,安定した二重構造を形成する. これらの合成分子は 核酸に似た 人工情報システムを作るのに 有望なことを示しています

科学分野:

  • 超分子化学
  • 有機化学
  • 材料科学

背景:

  • 合成情報分子の開発は 先進的な応用に不可欠です
  • フェニラセチレン背骨は複雑な分子構造を 構築するための多用途のプラットフォームを提供します
  • 水素結合は 生物学的システムにおける 重要な相互作用であり 合成模倣を促しています

研究 の 目的:

  • 特定の認識部位を持つフェニラセチレンオリゴーマーを合成し,特徴づけること.
  • 溶液中の多重H結合複合体の形成と安定性を研究する.
  • 合成情報伝達器としてのこれらのシステムの可能性を探求する.

主な方法:

  • オリゴーマー合成のためのソノガシラ結合
  • 浄化のための逆相製剤高圧液体染色学
  • 31P 核磁気共鳴 (NMR) によるデナチュレーション実験で,二重性の安定性を研究する.

主要な成果:

  • フェニラセチレンオリゴーマーをフェノールとフォスフィン酸化物の認識装置で成功して合成した.
  • 補完性オリゴマーの間の安定した多重H結合の形成が示された.
  • 量化された関連定数で,重複長さの増加に伴う重要な協力効果を示しています.

さらに関連する動画

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
10:41

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound

Published on: June 3, 2021

4.2K
Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
08:48

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

Published on: January 26, 2016

12.4K

関連する実験動画

Last Updated: Feb 5, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

10.4K
Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
10:41

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound

Published on: June 3, 2021

4.2K
Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
08:48

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

Published on: January 26, 2016

12.4K

結論:

  • フェニラセチレンオリゴマーは,協力的な分子間水素結合により,安定した拡張複合体を効果的に形成する.
  • 合成された超分子構造は 合成情報分子の開発の可能性を示しています
  • この研究は,核酸の機能を模倣する人工システムの設計を進めている.