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Chemical Dimerization-Induced Protein Condensates on Telomeres
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Photocaged-Photocleavable Chemical Dimerizer を使用して,生体細胞におけるタンパク質局所化の可逆的な制御

Chanat Aonbangkhen, Huaiying Zhang, Daniel Z Wu

    Journal of the American Chemical Society
    |September 11, 2018
    PubMed
    まとめ

    研究者らは,生物学的プロセスを正確に制御するために,タンパク質二重化 (CID) の新しい光活性化化学誘導体を開発しました. この新しいツールは,光を用いたタンパク質の相互作用の迅速なオン/オフを可能にし,細胞生物学の研究における空間時間的な解像度を高めます.

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