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Updated: Feb 5, 2026

A Human 3D Extracellular Matrix-Adipocyte Culture Model for Studying Matrix-Cell Metabolic Crosstalk
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細胞外マトリックスリモデリング TXNIP不安定化によるグルコース代謝を調節する

William J Sullivan1, Peter J Mullen2, Ernst W Schmid2

  • 1Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA.

Cell
|September 11, 2018
PubMed
まとめ

細胞外マトリックス改造は 細胞代謝を調節する ハイアロニダース治療は,TXNIPを分解し,細胞表面でのグルコーストランスポーターGLUT1を強化し,細胞移動を促進することによって,糖分分解を増加させます.

キーワード:
GLUT1の密輸TXNIPZFP36 について細胞生物学細胞の移動細胞外マトリックスグルコース代謝ハイアルロニダゼmRNAの分解受容体チロシンキナーゼシグナル伝達

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