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関連する概念動画

Assembly of Complex Microtubule Structures01:32

Assembly of Complex Microtubule Structures

2.4K
Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.
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Spindle Assembly02:50

Spindle Assembly

4.2K
Spindle assembly occurs through three, often coexisting, pathways – the centrosome-mediated pathway, the chromatin-mediated pathway, and the microtubule-mediated pathway – collectively contributing to form a robust spindle apparatus.
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a...
4.2K
Centrioles and Centrosomes01:13

Centrioles and Centrosomes

5.4K
Most animal cells comprise a pair of centrioles together called a centrosome. The cell duplicates its centrosome and contains two centrosomes side-by-side, which begin to move apart during the prophase. As the centrosomes migrate to two different sides of the cell, microtubules start extending from each centrosome toward the other end. The mitotic spindle is composed of the centrosomes and their emerging microtubules.
Near the end of the prophase, also called late prophase or...
5.4K
Microtubule Formation01:23

Microtubule Formation

7.4K
Microtubules are dynamic structures that undergo continuous assembly and disassembly. They originate from specialized multi-protein complexes known as microtubule organizing centers or MTOCs. Within the MTOC, the point of origin of the microtubule is known as the minus end, while the end radiating outward is the plus end. Microtubules serve two primary functions — the organization of spindle complexes to separate sister chromatids during mitotic or meiotic cell division and the formation...
7.4K
Microtubules in Cell Motility01:24

Microtubules in Cell Motility

4.5K
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
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Microtubule Associated Motor Proteins01:32

Microtubule Associated Motor Proteins

10.3K
Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they associate with, the direction they move within the cell, and the type of cargo they transport. Motor proteins that associate with microtubules are known as microtubule-associated motor proteins. There are two families of microtubule-associated motor proteins —Kinesins and Dyneins. Both these proteins assist in the transport of cellular...
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関連する実験動画

Updated: Jan 18, 2026

Assembly of Complex Microtubule Structures
01:32

Assembly of Complex Microtubule Structures

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ツールによるセンシングは,体外での感覚処理を拡張する.

Luke E Miller1,2,3, Luca Montroni4,5, Eric Koun4,5

  • 1Integrative Multisensory Perception Action & Cognition Team-ImpAct, Lyon Neuroscience Research Center, INSERM U1028, CNRS U5292, Lyon, France. luke.miller@inserm.fr.

Nature
|September 14, 2018
PubMed
まとめ

人間は道具を使って 物体の接触位置を感知し 身体の延長として扱います この感覚拡張は 機械的な道具の反応を 神経処理と統合して 精密な触覚知覚を実現します

さらに関連する動画

Spindle assembly: Dynein, Kinesin and Microtubules
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Spindle assembly: Dynein, Kinesin and Microtubules

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Centrioles and Centrosomes
01:13

Centrioles and Centrosomes

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関連する実験動画

Last Updated: Jan 18, 2026

Assembly of Complex Microtubule Structures
01:32

Assembly of Complex Microtubule Structures

2.4K
Spindle assembly: Dynein, Kinesin and Microtubules
02:50

Spindle assembly: Dynein, Kinesin and Microtubules

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Centrioles and Centrosomes
01:13

Centrioles and Centrosomes

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科学分野:

  • 神経科学
  • 人間 の 感覚 感知
  • 道具の使用

背景:

  • 動物は神経系を超えて感覚処理を行います (例えば,ネズミのひげ,クモの巣など)
  • 人間と道具のやり取りは 単純な機械的な操作と見なされます
  • ツールによる感覚情報の処理における 神経系の役割は完全に理解されていません.

研究 の 目的:

  • 人間が道具を 身体の感覚的な拡張物として扱っているかどうかを調べるため
  • ツールの使用中の触覚情報処理のメカニズムを探求する.
  • 直接的な身体的接触を超えた 感知を可能にするかどうかを判断する.

主な方法:

  • ツールによる触覚的局所化を評価する行動心理学の実験
  • 衝撃に対するツール反応の構造力学分析
  • タクティルアフェレンツとニューラルエンコーディングの計算モデル化

主要な成果:

  • 人間参加者は道具 (木製の棒) の物体の接触位置を正確に感知しました.
  • ツールの衝撃位置は,ツールのモダル応答 (前ニューロン処理) によってコード化されます.
  • 人間の行動を予測する 衝撃の場所の 急速なニューラル再コーディングを コンピューターモデルで示しました

結論:

  • ツールが神経系に組み込まれているのは 単なる受動的なリンクではなく 感覚の延長です
  • ツールによる触覚感知は 素材,生体力学,神経処理の 機能的な結合を伴うものです
  • この研究は,ツールにおけるニューロン前の機械的な情報符号化に関する証拠を提供する.