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Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria
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最適化されたアリロミシンは,グラム陰性抗生物質の新種である

Peter A Smith1, Michael F T Koehler2, Hany S Girgis3

  • 1Department of Infectious Diseases, Genentech, South San Francisco, CA, USA. smith.peter@gene.com.

Nature
|September 14, 2018
PubMed
まとめ

科学者たちは天然の産物である アリロミシンを最適化して 多剤耐性グラム陰性細菌に効く強力な抗生物質G0775を作りました この新薬は I型細菌のシグナルペプチダースを標的とし 耐性感染症と闘う新しいアプローチを 提供しています

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