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Updated: Feb 5, 2026

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
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飽和ゲノム編集によるBRCA1変異の正確な分類

Gregory M Findlay1, Riza M Daza1, Beth Martin1

  • 1Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Nature
|September 14, 2018
PubMed
まとめ

この研究では,BRCA1遺伝子変異体を分析するために,飽和ゲノム編集を使用した. この発見は,新たに特定された何千もの BRCA1 変異の乳がんと卵巣がんのリスクを分類するのに役立ちます.

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