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子供の Bronchiectasis: 診断と治療
Anne B Chang1, Andrew Bush2, Keith Grimwood3
1Child Health Division, Menzies School of Health Research, Casuarina, NT, Australia; Department of Respiratory Medicine, Children's Health Queensland, Brisbane, QLD, Australia; Queensland University of Technology, Brisbane, QLD, Australia.
Lancet (London, England)
|September 15, 2018
まとめ
早期診断と治療は 軽度の場合でも 肺機能の低下を止めることができます 非囊性線維症の小児支氣管切開の管理については,さらなる研究が必要である.
科学分野:
- 小児肺科
- 呼吸器医学
背景:
- ブロンキエクタシス,不可逆的な支障管の膨張は,世界中で,特に子供たちの慢性呼吸器疾患の重要な原因です.
- 小児の気管支障症の管理戦略には,しばしば高レベルの証拠が欠け,多くは成人またはキスティック線維症の研究から抽出されています.
- 幼児期における早期診断と早期介入は,小児性支気管症の管理に不可欠です.
研究 の 目的:
- 幼児における bronchiectasis の現在の知識と最新の定義を提示する.
- "治療可能な特徴"の概念を含む小児の支障管の管理における論争をレビューする.
- 非囊性線維症の気管切開の診断と管理における小児特有のデータの必要性を強調する.
主な方法:
- 既存の文献と診断における技術的進歩のレビュー
- 他の条件から抽出したものを含め,現在の管理戦略の分析.
- 小児の気管切開症における"治療可能な特徴"の概念についての議論.
主要な成果:
- 軽度の気管切除は,最初は不可逆的に見えたとしても,早期治療で回復し,肺機能の低下を阻止する可能性があります.
- 診断と管理のために,非胞性線維症の小児特異的なデータが必要であると認識されています.
- "治療可能な特徴"という概念は,小児の気管切開の管理に新しいアプローチを提供します.
結論:
- 軽度の場合でも,小児の気管切開の早期かつ最適な管理は,不可逆的な肺損傷を防ぐために重要です.
- 非囊性線維症の Bronchiectasisの効果的な診断と治療のために,小児特異的な証拠を生成するさらなる研究は不可欠です.
- "治療可能な特徴"のアプローチを採用することで, bronchiectasisを持つ子供たちの管理結果をパーソナライズし,改善することができます.
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