感覚,運動,そして学問は,ボリュームの皮質がない状態で
Y Kate Hong1, Clay O Lacefield1, Chris C Rodgers1
1Department of Neuroscience, Mortimer Zuckerman Mind Brain Behavior Institute and Kavli Institute for Brain Science, Columbia University, New York, NY, USA.
Nature
|September 19, 2018
まとめ
主要な体感皮質は,ひげを用いた物体検出には欠かせない. 脳の機能が回復した.
科学分野:
- 神経科学
- 感覚システム
- 脳皮質の機能
背景:
- 感覚検出における脳皮質の役割は議論されている.
- アクティブ・センシングは 協調した感覚と運動システムを含みます
研究 の 目的:
- 主要な体感皮質の必要性を調査する
- 感覚皮質の不活性化からの回復における経験の役割を探求する.
主な方法:
- オプトジェネティクスと永久的な病変を用いて マウスの主体感覚皮質を無効化しました
- 水の報酬として 顔のひげを使って 物体を検出する訓練を受けたマウス
- 不活性化後の行動回復とタスク獲得の評価
主要な成果:
- 無効化が検出を阻害し 感覚と運動のつながりを 強調した
- マウスは迅速に完全な行動能力を回復し 経験に依存した可塑性を示しました
- 学習前の消去は,タスクの獲得を妨げなかった.
結論:
- 主要な体感皮質は 活発なオブジェクト検出には不要かもしれません
- 他の脳の構造は 感覚皮質の損傷を補うことができます
- 経験と可塑性は 機能の迅速な回復を促します
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